World number one Andy Murray crashed out of the 2017 Australian Open after he was defeated by world number 50 Mischa Zverev of Germany in the fourth round.
Murray lost 5-7, 7-5, 2-6, 4-6 in three hours and 33 minutes.
The Brit has reached the finals of the tournament five times, but has always ended up on the losing side.
2017 Australian Open - Day 7 Updates!
Top two seeds out of tournament; a first since 2004
With Murray out, the top two seeds will be missing from rest of the tournament. The last time this has happened in a Grand Slam was at Roland Garros in 2004, when Roger Federer(1) and Andy Roddick(2) lost in the third and second round respectively.
Federer vs Nishikori
Federer survives against Nishikori; advances to quarter-finals
Swiss tennis legend Roger Federer defeated Japan's Kei Nishikori in five sets to advance to the quarter-finals of the 2017 Australian Open.
Federer won the match 6-7(4-7), 6-4, 6-1, 4-6, 6-3 in a three hour 23 minute intense battle.
He has now defeated two top-10 players in his last two outings in the tournament and will now face Germany's Mischa Zverev in the quarters.
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Kerber vs Vandeweghe
Top seeded Kerber knocked out
Women's top seed and defending champion Angelique Kerber faced a fourth round defeat from the hands of Coco Vandeweghe.
The German lost 2-6, 3-6 in straight sets in just one hour and eight minutes.
With that, the tournament has lost both top seeds and defending champions before the quarter-finals for the first time in an Open era.
Paes-Hingis advance, Mirza-Barbora out
Leander Paes and his Swiss partner Martina Hingis advanced into the second round of mixed doubles. The Indo-Swiss pair won 6-4, 6-3.
In women's doubles third round match, Sania Mirza and Barbora Strycova went down to Japanese pair 3-6, 6-2, 2-6 in one hour and 53 minutes.
Mihika Yadav registered a 6-3, 6-4 win in junior girls' singles round one match.
Tsonga, Wawrinka in last eight
France's Jo-Wilfried Tsonga defeated Britain's Daniel Evans 6-7(4-7), 6-2, 6-4, 6-4 in the fourth round of men's singles. In the other match, fourth seeded Stan Wawrinka won 7-6(7-2), 7-6(7-4), 7-6(7-4) against Italy's Andreas Seppi to advance in the last eight of the tournament.