Liverpool are unbeaten this season and have maintained a 100% win record.
Leicester have played well so far and are third on the table with 14 points.
It promises to be a cracking battle.
Here's the complete match preview.
What did the managers say ahead of the clash?
Leicester City manager Brendan Rodgers said he is happy for former club Liverpool. "I am the type of person who is happy for the club and especially happy for players like Jordan [Henderson] and James Milner - players I worked with and had a strong relationship with."
Meanwhile, Jurgen Klopp said, "He (Rodgers) is doing really well. I am not surprised about that."
Team news and selection
Liverpool will take a late call on fit-again goal-keeper Alisson. Central defender Joel Matip has been ruled out, whereas, Xherdan Shaqiri is also an absentee. For Leicester, James Maddison is set to return after missing out last weekend against Newcastle.
Stat attack: Liverpool vs Leicester
The Reds are unbeaten in their last 43 home league games. This is the longest current run in the top five European leagues.
Liverpool have also won16 consecutive league matches.
This is Leicester boss Rodgers' first return to Anfield since leaving the Reds in October 2015.
Liverpool are unbeaten in eight Premier League matches at home against Leicester.
Dream11: Mane, Vardy lead a strong side on offer
We have gone with Kasper Schmeichel as the goal-keeper given the uncertainty of who will start for Liverpool in goal.
Trent Alexander-Arnold, Andrew Robertson, Ben Chilwell and Virgil van Dijk are the four defenders.
The three-man mid-field sees Georginio Wijnaldum, Youri Tielemans and Wilfred Ndidi feature.