Written byRajdeep Saha
The winner between the two teams will meet Arsenal in the final, who overcame Manchester City.
United have beaten Chelsea in three games across competitions this season and will hope to maintain a 100% record.
Here's the match preview.
Manchester United will see Luke Shaw miss the game after he failed to recover from an ankle injury.
However, Brandon Williams could feature after a facial injury.
For Chelsea, N'Golo Kante will miss a fourth successive game because of a hamstring injury.
Meanwhile, Billy Gilmour, 19, is out for the remainder of the season following knee surgery.
United have done relatively well of late and are also unbeaten in 19 games across competitions.
They need to take the game to Chelsea and be solid all around the pitch.
The Blues could be a suspect in their defensive offerings and that's where United need to cash in.
Chelsea are strong going forward and will cause problems for the Red Devils.
The sides are meeting for the fourth season in a row in the FA Cup.
The Blues won the quarter-final clash in 2017 and the final in 2018, whereas, United claimed victory in the fifth round last season.
United are vying to go seven games unbeaten against Chelsea.
United are playing in their 30th FA Cup semi-final.
Dream11 team prediction (4-3-3): Romero; Wan-Bisakka, Maguire, Azpilicueta, Alonso; Fernandes (c), Matic, Jorginho; Martial, Giroud (vc), Pulisic.
The match is set to start at 10:30 PM IST.
One can watch the match live on the Sony Ten Network and stream the same on Sony Liv app (paid subscription).
Match prediction: 2-1.
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