A tanker crashed into the river cruise ship American Heritage on the Mississippi River in New Orleans around midday Friday.
The impact caused the ship to take on water and tilt to one side, while more than 130 people were on board.
Rescue teams work with local officials
Rescue teams rushed in right away, working alongside local officials after Louisiana's governor confirmed the accident.
Early reports suggest the tanker may have lost power before hitting the cruise ship.
Rescue efforts are underway to rescue people from the water.