IIT Bombay scientists develop KTDP peptide lowering LDL and triglycerides
Technology
Scientists at IIT Bombay have created a peptide called KTDP that can seriously lower bad LDL cholesterol and triglycerides.
Unlike regular statins, KTDP works by blocking how fats move inside liver cells, stopping them from reaching the bloodstream, and sending them to be burned for energy instead.
KTDP targets kinesin-1, halves lipid release
KTDP targets a protein called kinesin-1, which usually helps transport fat in liver cells.
In lab tests and on zebrafish, it cut cholesterol and triglyceride release by about one-half.
The team has filed for a patent, and animal studies are up next before any human trials.
Their research just got published in the journal Proceedings of the National Academy of Sciences.