Alzheimer's, Parkinson's linked by same brain cell communication issue
Scientists in Japan have found that both Alzheimer's and Parkinson's are driven by a similar problem: misfolded proteins messing with how brain cells talk to each other.
These proteins—called tau in Alzheimer's and -synuclein in Parkinson's—build up at the connections between neurons, causing trouble for brain function.
The discovery could help researchers find new ways to treat both diseases.
Boosting brain's natural recycling process might help clear out protein clumps
The team also found that boosting the brain's natural recycling process (autophagy) might help clear out these protein clumps and restore neuron communication.
This opens up new ideas for therapies—like stopping protein buildup, controlling microtubule production, or blocking harmful interactions—which could make a real difference for people living with these conditions.