New RNA drug could help your body repair itself after heart attacks
Scientists at Cedars-Sinai have created an experimental RNA drug called TY1 that helps fix DNA damage and support tissue repair after heart attacks or inflammation.
TY1 is the first in a new group of drugs called "exomers," inspired by natural molecules from heart cells.
After promising results in animals, clinical trials are planned as the next step.
How does TY1 actually work?
TY1 boosts a gene called TREX1 in immune cells (macrophages) that clean up damaged DNA and calm inflammation.
In animal tests, this meant less heart damage, less scarring, and better recovery after a heart attack.
It even showed potential for treating autoimmune diseases—plus, it worked safely in animal studies whether taken as a shot or a pill.
Why does this matter?
If TY1 proves safe in people, it could change how we treat not just heart injuries but other diseases linked to DNA damage.
Basically, it helps your body tap into its own repair system—a pretty exciting step for future medicine.