New gene therapy could help people lose weight
Scientists are testing a new gene therapy that could help people lose weight and manage diabetes by getting their own cells to make GLP-1—a hormone that curbs hunger and controls blood sugar.
The hope is for a one-time treatment, so no more regular injections like current meds.
Trials show significant weight loss in obese mice
In trials, obese mice given the therapy dropped up to 20% of their body weight within weeks.
The approach—using viruses or electrical pulses to deliver DNA—also improved blood sugar and are being tested in bigger animals like pigs and monkeys.
GLP-1 drugs already in use
GLP-1 drugs are already helping lower obesity rates and protect against heart and kidney issues.
Gene therapy could mean longer-lasting effects without repeat doses, but because it's permanent, scientists want thorough safety checks before trying it in people.