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Technology Jun 26, 2025

Groundbreaking obesity trial reveals promising results

MariTide, Amgen's once-a-month injection, helped adults with obesity lose up to 20% of their body weight in a year-long trial.
For those with both obesity and Type 2 diabetes, the average weight loss was about 17%.
The shot could make managing weight and health a lot more convenient.

TL;DR

Many people saw better blood sugar control

Besides dropping pounds, many people saw better blood sugar control (lower HbA1c), smaller waists, improved blood pressure, and healthier cholesterol.
Upside: lots of health wins.
Downside: stomach issues were common but usually got better by starting on lower doses.

Amgen is now testing a slower dose increase

Because some people stopped early due to side effects, Amgen is now testing a slower dose increase in bigger trials.
They're also checking if MariTide keeps working long-term and how it affects heart and metabolic health overall.