HIV treatment: Antibody effectiveness varies by region, study finds

Technology Nov 08, 2025

A new study from India just found that HIV antibody treatments don't work the same everywhere—they actually depend on where the virus comes from.
This challenges the old idea that broadly-neutralizing antibodies (bnAbs) are a universal fix, especially for common strains like HIV-1 Clade C in Africa and India.

Study suggests local strain-specific therapies needed

Researchers tested bnAbs on HIV strains from nine regions across India and saw big differences in how well they worked.
About 11% of patients already had some resistance before treatment even started.
Dr. Jayanta Bhattacharya says it's time to focus on therapies designed for local strains, and combining bnAbs with standard antiretroviral drugs could help fight tougher cases—especially for high-risk groups.