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Technology Jun 30, 2025

IISc develops glowing sensor for liver cancer detection

Scientists at IISc have come up with a simple paper sensor that can help catch liver cancer and some other diseases early.
It works by lighting up bright green under UV light if it finds b-glucuronidase, an enzyme linked to these conditions.

TL;DR

How the sensor works

The team embedded terbium (a rare earth metal) and special chemicals into tiny paper disks.
When the target enzyme is present, it triggers a chain reaction that makes the disk glow brighter—the more enzyme, the stronger the glow.
You just need a UV lamp and free software to check the results.

Could transform testing in low-resource settings

This sensor can pick up super-low levels of the enzyme—way below what's usually needed for diagnosis—and doesn't require fancy lab gear.
It could be a game-changer for quick, affordable testing in places that don't have high-tech labs.
Plus, it might help detect not just liver cancer but also jaundice or drug toxicity where this enzyme spikes.