Major genetic study reveals biological roots of ME/CFS
The DecodeME study—using DNA from over 15,500 people with ME/CFS and 250,000 controls—has found eight genetic regions tied to higher risk for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
This is the largest genetic study on ME/CFS so far and suggests these gene variants might weaken immune defenses and cause symptoms like constant pain.
Research shows multiple genetic factors raise ME/CFS risk
Instead of a single cause, DecodeME's deep dive into genomic sites revealed several genetic factors that raise the risk of ME/CFS.
This is solid proof that ME/CFS is rooted in biology—not just "in your head" or caused by lifestyle choices.
Findings challenge old stigma around ME/CFS
These findings back up what patients have been saying for years, helping push back against the old stigma around ME/CFS.
Plus, this research has created a significant resource for future studies—including looking at links with things like COVID-19.
Research could lead to new treatments for ME/CFS
DecodeME's discoveries could lead to new ways to diagnose and treat ME/CFS.
For millions living with this condition worldwide, it's a hopeful step toward better care and understanding what really causes it.