New RNA-based injection could help you lose weight

Technology Sep 22, 2025

A new weekly injection called RES-010 is being tested in the Netherlands to help people lose weight and keep it off.
Developed by Resalis Therapeutics, this RNA-based treatment started its first human trial in November 2024.
Early results on safety and effectiveness are expected by early 2026.

RES-010 works by boosting your body's fat-burning ability

RES-010 works differently from popular drugs like Ozempic—it doesn't just curb your appetite. Instead, it targets a molecule called miR-22 to boost how your body burns fat and energy.
In animal studies, mice lost 12% more weight without eating less, and primates saw a 15% drop in fat with almost no muscle loss.
The aim is steady fat loss while keeping muscle and bone healthy—something current options often struggle with.