Newsbytes
  • India
  • Business
  • World
  • Politics
  • Sports
  • Technology
  • Entertainment
  • Auto
  • Lifestyle
  • Inspirational
  • Career
  • Bengaluru
  • Delhi
  • Mumbai
  • Videos
  • Visual Stories
  • Reviews
  • Phone Reviews
  • Fitness Bands Reviews
  • Speakers Reviews
  • Find Cricket Statistics
Hindi
More
In the news
Samsung
Elon Musk
Apple
Newsbytes
Hindi
Newsbytes
User Placeholder

Hi,

Logout


India
Business
World
Politics
Sports
Technology
Entertainment
Auto
Lifestyle
Inspirational
Career
Bengaluru
Delhi
Mumbai
Videos
Visual Stories
Reviews
Phone Reviews
Fitness Bands Reviews
Speakers Reviews
Find Cricket Statistics

More Links
  • Videos

Download Android App

Follow us on
  • Facebook
  • Twitter
  • Linkedin
  • Youtube
 
Home / News / Technology News / New potential breast cancer drug identified
Technology

New potential breast cancer drug identified

New potential breast cancer drug identified
Written by Astha Oriel
Dec 19, 2020, 12:58 pm 2 min read
New potential breast cancer drug identified

Scientists have identified a molecule that can help treat breast cancer, giving hope to patients who have become resistant to traditional therapies. The first-in-class molecule shuts down estrogen-sensitive breast cancer in a new way, researchers said. First-in-class drugs are those that work by a unique mechanism - in this case, a molecule that targets a protein on the oestrogen receptor of tumour cells.

Details
Overcomes limitations of current therapies: UT Southwestern Professor

Ganesh Raj, professor at the University of Texas Southwestern (UT Southwestern) Simmons Cancer Center said, "This is a fundamentally different, new class of agents for estrogen-receptor-positive breast cancer. Its unique mechanism of action overcomes the limitations of current therapies." He further said, "The new compound is a potential highly effective, next-line treatment for these patients."

Information
How does the new drug work?

The drug works by blocking other molecules - proteins called co-factors - that also must attach to the estrogen receptor for cancer cells to multiply. The new molecule, dubbed ERX-11, mimics a peptide, or protein building block.

Background
Why treatment drugs fail to work over time?

Traditional hormonal drugs work by attaching to a molecule called the estrogen receptor in cancer cells, preventing estrogen from binding to the receptor, a necessary step for cancer cells to multiply. However, the estrogen receptor can mutate and change its shape over time so that the treatment drug no longer fits neatly with the receptor leading to the multiplication of cancer cells again.

Research
Blocking "protein-protein interactions" dream for cancer researchers

David Mangelsdorf, professor at UT Southwestern said, "There has been intense interest in developing drugs that block the ability of the estrogen receptor - the prime target in most breast cancers - from interacting with the co-regulator proteins that cause a tumor's growth." "Blocking such 'protein-protein interactions' has been a dream of cancer researchers for decades," he added.

Share this timeline
Facebook
Whatsapp
Twitter
Linkedin
Astha Oriel
Astha Oriel
Twitter
I am a graduate of the Indian Institute of Journalism and New Media, Bangalore. As a history buff, I am an avid reader. When I am not reading, I like to listen to classical Hollywood and Bollywood songs, learn a new language, or doodle.
Latest
Health & Wellness
Related
Latest
Samsung Galaxy A13 5G's European prices tipped; launch imminent
Samsung Galaxy A13 5G's European prices tipped; launch imminent Technology
Your guide to traveling to Dalhousie
Your guide to traveling to Dalhousie Lifestyle
Decoding Rohit Sharma's abysmal numbers in IPL 2022
Decoding Rohit Sharma's abysmal numbers in IPL 2022 Sports
2022 Benelli TRK 502 range arrives with more features
2022 Benelli TRK 502 range arrives with more features Auto
For the love of baking: Must-know cake frosting recipes
For the love of baking: Must-know cake frosting recipes Lifestyle
Health & Wellness
5 theories on why we dream
5 theories on why we dream Lifestyle
International Tea Day: Exploring India's position in the global market
International Tea Day: Exploring India's position in the global market Lifestyle
International Tea Day: 5 herbal teas and their benefits
International Tea Day: 5 herbal teas and their benefits Lifestyle
5 workout essentials to carry in your gym bag
5 workout essentials to carry in your gym bag Lifestyle
Common pregnancy cravings and what do they mean
Common pregnancy cravings and what do they mean Lifestyle
More News
Related
Tollywood actress Hamsa Nandini opens up about cancer diagnosis
Tollywood actress Hamsa Nandini opens up about cancer diagnosis Entertainment
Next News Article
Next News Article

Love Technology news?

Subscribe to stay updated.

Science Thumbnail
India News Business News World News Politics News Sports News Technology News Entertainment News Auto News Lifestyle News Inspirational News
Career News Bengaluru News Delhi News Mumbai News Mukesh Ambani Indian Premier League (IPL) Karnataka Samsung Xiaomi West Bengal
Bihar Virat Kohli Rohit Sharma Haryana Narendra Modi Arvind Kejriwal Tamil Nadu Gujarat Yogi Adityanath YouTube
Instagram Hollywood News Uttar Pradesh Kerala Netflix Bollywood News Mamata Banerjee Maruti Suzuki Rahul Gandhi Elon Musk
Shah Rukh Khan Chelsea FC OPPO Akhilesh Yadav Indian Cricket Team Apple Manchester United Salman Khan Cryptocurrency OnePlus
Amitabh Bachchan ICC Women's World Cup Vivo India vs Sri Lanka
About Us Privacy Policy Terms & Conditions Contact Us Ethical Conduct Grievance Redressal News News Archive Topics Archive IPL 2022 Schedule IPL 2022 Points Table Find Cricket Statistics
Follow us on
Facebook Twitter Linkedin Youtube
All rights reserved © NewsBytes 2022