One-time gene therapy could replace daily cholesterol meds

Technology Nov 11, 2025

Scientists just tested a single CRISPR-Cas9 infusion on 15 people with stubborn lipid disorders—and the results are impressive.
After one IV dose, patients saw their LDL cholesterol drop by about 50% and triglycerides fall by about 55% after 60 days at the highest dose, with these effects sticking around for at least two months.
No serious side effects popped up during the trial.

If this 1-time treatment holds up in bigger studies

Heart disease is still the world's top killer, and some folks can't get their cholesterol down even with daily meds or monthly shots.
If this one-time treatment holds up in bigger studies, it could mean ditching constant pills for lasting results—making life a lot easier for anyone struggling to keep their heart healthy.