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Home / News / Technology News / Moderna's COVID-19 vaccine found to be 95% effective: Details here
Technology

Moderna's COVID-19 vaccine found to be 95% effective: Details here

Moderna's COVID-19 vaccine found to be 95% effective: Details here
Written by Ramya Patelkhana
Nov 16, 2020, 07:54 pm 3 min read
Moderna's COVID-19 vaccine found to be 95% effective: Details here
Credits:

American biotech company Moderna Therapeutics has announced that its COVID-19 vaccine was found to be nearly 95% effective in preventing the novel coronavirus disease. The company released the preliminary results from the Phase 3 clinical trials of its experimental COVID-19 vaccine on Monday. These trials are conducted in humans in order to assess the safety and efficacy of a vaccine. Here are more details.

Details
Researchers found the vaccine had efficacy of 94.5%

The findings are based on Moderna's trial in the US involving 30,000 people split into two groups—one group received two doses of the shot, while the other was given a placebo. The researchers found that based on data from 95 participants who developed COVID-19 symptoms, the vaccine had 94.5% efficacy. Of them, 90 were given the placebo, and the remaining five received the vaccine.

Findings
No severe COVID-19 cases in people who were immunized

According to Moderna, of the 95 confirmed cases of COVID-19 during the trial, 11 were severe ones. However, none of the severe cases occurred in people who received the vaccine. This development comes days after Pfizer and the German firm BioNTech announced that their vaccine candidate is 90% effective. Notably, Moderna's vaccine is also based on a similar mRNA technology as the Pfizer/BioNTech vaccine.

Twitter Post
Here's what Moderna tweeted on the development

We just announced that mRNA-1273, our COVID-19 vaccine candidate, has met its primary efficacy endpoint in the first interim analysis of the Phase 3 COVE study.
Read more: https://t.co/vYWEy8CKCv pic.twitter.com/YuLubU1tlx

— Moderna (@moderna_tx) November 16, 2020
The US
Moderna to apply for EUA from FDA in coming weeks

Moderna said it plans to approach the US Food and Drug Administration (FDA), in the coming weeks, for an emergency-use authorization (EUA) for its vaccine. However, its vaccine is unlikely to be available outside the US until next year. The company is projected to have 20 million doses ready in America by 2020-end, and manufacture 500 million to 1 billion doses globally in 2021.

Safety
No significant safety concerns, shows safety data

Interestingly, Moderna said that the safety data available for its vaccine indicated no significant safety concerns. On the other hand, side effects observed in the interim analysis reportedly included pain at the injection site, fatigue, and aching muscles and joints. "This is a pivotal moment in the development of our COVID-19 vaccine candidate," said Stephane Bancel, Chief Executive Officer of Moderna, in a statement.

Statement
First clinical validation that our vaccine can prevent COVID-19: Bancel

"Since early January, we have chased this virus with the intent to protect as many people around the world as possible. All along, we have known that each day matters," said Bancel. "This positive interim analysis from our Phase 3 study has given us the first clinical validation that our vaccine can prevent COVID-19 disease, including severe disease," he added.

Cost
What about the cost?

The cost for Moderna's two-shot course is, however, more expensive compared to other vaccine forerunners, reports say. Moderna's vaccine is likely to cost around £38-45 (approximately Rs. 3,730-4,420), while Pfizer's two-shot course is expected to cost £30 (Rs. 2,950). The Oxford University-AstraZeneca shot might cost £3 (Rs. 295), while both Johnson & Johnson and Sanofi-GSK vaccine candidates are expected to cost £8 (Rs. 785).

Advantage
Moderna's vaccine has major advantage over the Pfizer shot

Despite being costlier than Pfizer's vaccine, Moderna's shot would have a major advantage in terms of shelf-life and stability. Pfizer's vaccine must be stored between -70C and -80C, which might pose logistical challenges. But Moderna's vaccine is easier to store and distribute. It can be stored at standard refrigeration temperatures of 2-8C for 30 days, and at -20C for six months for shipping/long-term storage.

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Ramya Patelkhana
Ramya Patelkhana
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Ramya Patelkhana is a senior editor at NewsBytes. She has nearly seven years of experience in digital journalism and has previously worked with India News and Authint Media. She has a Bachelor's degree in Journalism and Mass Communication from the IK Gujral Punjab Technical University, Kapurthala, and an advanced diploma in Media Studies from IPW, New Delhi.
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